Table 1.

Genes significantly changed in expression upon imatinib treatment for 4 hours

GIST-T1GIST882
Gene symbolLog2 fold changeFDRLog2 fold changeFDR
SPRY4−5.30−7.40
EGR1−5.30−6.20
PTGS2−3.80−5.20
DUSP4−2.30−4.51.0 × 10−187
DUSP6−4.10−4.20
FOS−3.11.3 × 10−40−3.61.2 × 10−47
C3orf80−2.21.1 × 10−21−3.52.3 × 10−248
C11orf96−2.19.1 × 10−212−3.44.0 × 10−181
TBX2−2.50−3.38.7 × 10−131
GPR3−4.39.2 × 10−65−3.19.2 × 10−105
TMEM100−3.70−2.91.3 × 10−20
RAPGEF5−2.40−2.92.6 × 10−71
DUSP5−4.49.6 × 10−188−2.86.0 × 10−89
FOSL1−2.51.5 × 10−15−2.88.7 × 10−60
IBA57−3.00−2.77.4 × 10−231
PTPRE−2.45.5 × 10−157−2.75.4 × 10−36
CCL2−2.61.6 × 10−90−2.63.7 × 10−31
PLK3−4.06.2 × 10−132−2.53.9 × 10−27
MFSD2A−2.21.2 × 10−14−2.43.6 × 10−30
LINC00961−2.29.5 × 10−10−2.23.8 × 10−23
SPRY2−2.90−2.21.4 × 10−172
ADAMTS52.11.2 × 10−2502.29.0 × 10−20
GPR1462.73.2 × 10−282.57.5 × 10−32
FAXDC23.102.55.2 × 10−61
BMF2.802.71.2 × 10−67
KLHL383.26.9 × 10−2473.71.8 × 10−27
FBXO324.003.85.4 × 10−130