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Volume 10, Issue 1, pp. 104-123
PubMed
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History
- Received August 30, 2019
- Revision received October 17, 2019
- Accepted October 18, 2019
- Published first October 24, 2019.
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- Previous version (October 24, 2019 - 06:10).
- Previous version (December 18, 2019 - 05:59).
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©2019 American Association for Cancer Research.
Author Information
- G. Aaron Hobbs1,
- Nicole M. Baker1,
- Anne M. Miermont2,
- Ryan D. Thurman3,
- Mariaelena Pierobon4,
- Timothy H. Tran5,
- Andrew O. Anderson2,
- Andrew M. Waters6,
- J. Nathaniel Diehl7,
- Bjoern Papke6,
- Richard G. Hodge6,
- Jennifer E. Klomp6,
- Craig M. Goodwin6,
- Jonathan M. DeLiberty1,
- Junning Wang8,
- Raymond W.S. Ng8,
- Prson Gautam9,
- Kirsten L. Bryant1,
- Dominic Esposito5,
- Sharon L. Campbell3,6,
- Emanuel F. Petricoin III4,
- Dhirendra K. Simanshu5,
- Andrew J. Aguirre8,10,
- Brian M. Wolpin8,
- Krister Wennerberg9,11,
- Udo Rudloff2,12,*,
- Adrienne D. Cox1,6,13 and
- Channing J. Der1,6,7,*
- 1Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
- 2Thoracic and GI Oncology Branch, NCI, Bethesda, Maryland.
- 3Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
- 4Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, Virginia.
- 5NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, Maryland.
- 6Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
- 7Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
- 8Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
- 9Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
- 10Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
- 11Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark.
- 12Rare Tumor Initiative, Pediatric Oncology Branch, NCI, Bethesda, Maryland.
- 13Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
- ↵*Corresponding Authors:
Channing J. Der, University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, CB7295, Chapel Hill, NC 27599-7295. Phone: 919-966-5634; Fax: 919-966-9673; E-mail: cjder{at}med.unc.edu; and Udo Rudloff, Center for Cancer Research, NCI, Building 10, Hatfield CRC, Room 2B-34D, Bethesda, MD 20892. Phone: 240-760-6238; E-mail: rudloffu{at}mail.nih.gov
January 2020
Volume 10, Issue 1
Volume 10, Issue 1
Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer
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