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MAIT Cells Promote Tumor Initiation, Growth, and Metastases via Tumor MR1

Juming Yan, Stacey Allen, Elizabeth McDonald, Indrajit Das, Jeffrey Y.W. Mak, Ligong Liu, David P. Fairlie, Bronwyn S. Meehan, Zhenjun Chen, Alexandra J. Corbett, Antiopi Varelias, Mark J. Smyth and Michele W.L. Teng
Juming Yan
1Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston, Australia.
2School of Medicine, University of Queensland, Herston, Australia.
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  • ORCID record for Juming Yan
Stacey Allen
1Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston, Australia.
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Elizabeth McDonald
1Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston, Australia.
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  • ORCID record for Elizabeth McDonald
Indrajit Das
3Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Australia.
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Jeffrey Y.W. Mak
4Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia.
5ARC Centre of Excellence in Advanced Molecular Imaging, University of Queensland, Brisbane, Australia.
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Ligong Liu
4Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia.
5ARC Centre of Excellence in Advanced Molecular Imaging, University of Queensland, Brisbane, Australia.
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David P. Fairlie
4Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia.
5ARC Centre of Excellence in Advanced Molecular Imaging, University of Queensland, Brisbane, Australia.
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Bronwyn S. Meehan
6Department of Microbiology and Immunology, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Victoria, Australia.
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Zhenjun Chen
6Department of Microbiology and Immunology, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Victoria, Australia.
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Alexandra J. Corbett
6Department of Microbiology and Immunology, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Victoria, Australia.
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  • ORCID record for Alexandra J. Corbett
Antiopi Varelias
2School of Medicine, University of Queensland, Herston, Australia.
7Transplantation Immunology Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
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Mark J. Smyth
2School of Medicine, University of Queensland, Herston, Australia.
3Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Australia.
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Michele W.L. Teng
1Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston, Australia.
2School of Medicine, University of Queensland, Herston, Australia.
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  • For correspondence: michele.teng@qimrberghofer.edu.au
DOI: 10.1158/2159-8290.CD-19-0569 Published January 2020
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ARTICLE USAGE: October 2019 to January 2021

AbstractFull-text HTMLPDF
Total1035012792569

Cited By

Article Information

Volume 10, Issue 1, pp. 124-141

DOI 
https://doi.org/10.1158/2159-8290.CD-19-0569
PubMed 
31826876

Published By 
American Association for Cancer Research
Print ISSN 
2159-8274
Online ISSN 
2159-8290
History 
  • Received May 18, 2019
  • Revision received September 9, 2019
  • Accepted October 18, 2019
  • Published first December 11, 2019.

Article Versions

  • Previous version (December 11, 2019 - 06:30).
  • Previous version (December 18, 2019 - 05:59).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2019 American Association for Cancer Research.

Author Information

  1. Juming Yan1,2,
  2. Stacey Allen1,
  3. Elizabeth McDonald1,
  4. Indrajit Das3,
  5. Jeffrey Y.W. Mak4,5,
  6. Ligong Liu4,5,
  7. David P. Fairlie4,5,
  8. Bronwyn S. Meehan6,
  9. Zhenjun Chen6,
  10. Alexandra J. Corbett6,
  11. Antiopi Varelias2,7,
  12. Mark J. Smyth2,3 and
  13. Michele W.L. Teng1,2,*
  1. 1Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston, Australia.
  2. 2School of Medicine, University of Queensland, Herston, Australia.
  3. 3Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Australia.
  4. 4Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia.
  5. 5ARC Centre of Excellence in Advanced Molecular Imaging, University of Queensland, Brisbane, Australia.
  6. 6Department of Microbiology and Immunology, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Victoria, Australia.
  7. 7Transplantation Immunology Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  1. ↵*Corresponding Author:
    Michele W.L. Teng, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Queensland 4006, Australia. Phone: 617-3845-3958; Fax: 617-3362-0111; E-mail: michele.teng{at}qimrberghofer.edu.au
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Cancer Discovery: 10 (1)
January 2020
Volume 10, Issue 1
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MAIT Cells Promote Tumor Initiation, Growth, and Metastases via Tumor MR1
Juming Yan, Stacey Allen, Elizabeth McDonald, Indrajit Das, Jeffrey Y.W. Mak, Ligong Liu, David P. Fairlie, Bronwyn S. Meehan, Zhenjun Chen, Alexandra J. Corbett, Antiopi Varelias, Mark J. Smyth and Michele W.L. Teng
Cancer Discov January 1 2020 (10) (1) 124-141; DOI: 10.1158/2159-8290.CD-19-0569

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MAIT Cells Promote Tumor Initiation, Growth, and Metastases via Tumor MR1
Juming Yan, Stacey Allen, Elizabeth McDonald, Indrajit Das, Jeffrey Y.W. Mak, Ligong Liu, David P. Fairlie, Bronwyn S. Meehan, Zhenjun Chen, Alexandra J. Corbett, Antiopi Varelias, Mark J. Smyth and Michele W.L. Teng
Cancer Discov January 1 2020 (10) (1) 124-141; DOI: 10.1158/2159-8290.CD-19-0569
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