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Abstract
Four recent studies help explain why extrachromosomal DNA, with its many oncogene amplifications and circular shape, is such a potent driver of tumor growth. The start-up company Boundless Bio aims to apply these insights to the treatment of intractable cancers in which extra loops of DNA are abundant.
- ©2020 American Association for Cancer Research.
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February 2020
Volume 10, Issue 2
Volume 10, Issue 2
Circular DNA Throws Gene Regulation for a Loop
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