The COVID-19 pandemic has raised questions about the impact of the disease on patients with cancer, who are generally more susceptible to infections. Dai and colleagues report the results of a multicenter study in Wuhan, China, comparing patients with cancer to age-matched controls, all diagnosed with COIVD-19. Substantial differences in prognosis based on cancer stage and type emerged: Stage IV cancer conferred a much worse prognosis than non-metastatic cancer, and patients with hematologic or lung malignancies were most at risk for severe complications of COVID-19. For details, please see the article by Dai and colleagues on page 783. Additional coverage of the relationship between COVID-19 and cancer can be found in the News and In Focus sections of this issue.