Skip to main content
  • AACR Publications
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

AACR logo

  • Register
  • Log in
  • My Cart
Advertisement

Main menu

  • Home
  • About
    • The Journal
    • AACR Journals
    • Journal Sections
    • Subscriptions
    • Permissions and Reprints
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • Collections
      • COVID-19 & Cancer Resource Center
      • Precision Medicine and Therapeutic Resistance
      • Clinical Trials
      • Immuno-oncology
      • Editors' Picks
      • "Best of" Collection
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citation
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
    • Journal Press Releases
  • COVID-19
  • Webinars
  • 10th Anniversary
  • Search More

    Advanced Search

  • AACR Publications
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

User menu

  • Register
  • Log in
  • My Cart

Search

  • Advanced search
Cancer Discovery
Cancer Discovery
  • Home
  • About
    • The Journal
    • AACR Journals
    • Journal Sections
    • Subscriptions
    • Permissions and Reprints
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • Collections
      • COVID-19 & Cancer Resource Center
      • Precision Medicine and Therapeutic Resistance
      • Clinical Trials
      • Immuno-oncology
      • Editors' Picks
      • "Best of" Collection
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citation
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
    • Journal Press Releases
  • COVID-19
  • Webinars
  • 10th Anniversary
  • Search More

    Advanced Search

Table of Contents

Editorial

  • Editorial | Free Article
    A Decade of Cancer Discovery
    Luis A. Diaz and Lewis C. Cantley
    Cancer Discov April 1 2021 11 (4) 795-797; DOI:10.1158/2159-8290.CD-21-0082

In Focus

  • In Focus
    T Cells as the Future of Cancer Therapy
    Antoni Ribas
    Cancer Discov April 1 2021 11 (4) 798-800; DOI:10.1158/2159-8290.CD-21-0022

  • In Focus
    Fighting the Sixth Decade of the Cancer War with Better Cancer Models
    David A. Tuveson
    Cancer Discov April 1 2021 11 (4) 801-804; DOI:10.1158/2159-8290.CD-21-0234

  • In Focus
    Genomics and Cancer Disparities: The Justice and Power of Inclusion
    Melissa B. Davis
    Cancer Discov April 1 2021 11 (4) 805-809; DOI:10.1158/2159-8290.CD-21-0225

  • In Focus
    The Promising Evolution of Targeted Therapeutic Strategies in Cancer
    Solange Peters, Tony Mok, Antonio Passaro and Pasi Antero Jänne
    Cancer Discov April 1 2021 11 (4) 810-814; DOI:10.1158/2159-8290.CD-21-0124

Perspective

  • Perspective
    Emerging Trends in Cancer Drug Discovery—From Drugging the “Undruggable” to Overcoming Resistance
    Joachim Rudolph, Jeff Settleman and Shiva Malek
    Cancer Discov April 1 2021 11 (4) 815-821; DOI:10.1158/2159-8290.CD-21-0260

Reviews

  • Reviews
    The Future of Clinical Trial Design in Oncology
    Anna Spreafico, Aaron R. Hansen, Albiruni R. Abdul Razak, Philippe L. Bedard and Lillian L. Siu
    Cancer Discov April 1 2021 11 (4) 822-837; DOI:10.1158/2159-8290.CD-20-1301

  • Reviews
    The Next Decade of Immune Checkpoint Therapy
    Padmanee Sharma, Bilal A. Siddiqui, Swetha Anandhan, Shalini S. Yadav, Sumit K. Subudhi, Jianjun Gao, Sangeeta Goswami and James P. Allison
    Cancer Discov April 1 2021 11 (4) 838-857; DOI:10.1158/2159-8290.CD-20-1680

  • Reviews
    Liquid Biopsy: From Discovery to Clinical Application
    Catherine Alix-Panabières and Klaus Pantel
    Cancer Discov April 1 2021 11 (4) 858-873; DOI:10.1158/2159-8290.CD-20-1311

  • Reviews
    Overcoming Resistance to Tumor-Targeted and Immune-Targeted Therapies
    Mihaela Aldea, Fabrice Andre, Aurelien Marabelle, Semih Dogan, Fabrice Barlesi and Jean-Charles Soria
    Cancer Discov April 1 2021 11 (4) 874-899; DOI:10.1158/2159-8290.CD-20-1638

  • Reviews
    Artificial Intelligence in Cancer Research and Precision Medicine
    Bhavneet Bhinder, Coryandar Gilvary, Neel S. Madhukar and Olivier Elemento
    Cancer Discov April 1 2021 11 (4) 900-915; DOI:10.1158/2159-8290.CD-21-0090

  • Reviews
    Tracking Cancer Evolution through the Disease Course
    Chris Bailey, James R.M. Black, James L. Reading, Kevin Litchfield, Samra Turajlic, Nicholas McGranahan, Mariam Jamal-Hanjani and Charles Swanton
    Cancer Discov April 1 2021 11 (4) 916-932; DOI:10.1158/2159-8290.CD-20-1559

  • Reviews
    Therapeutic Targeting of the Tumor Microenvironment
    Leire Bejarano, Marta J.C. Jordāo and Johanna A. Joyce
    Cancer Discov April 1 2021 11 (4) 933-959; DOI:10.1158/2159-8290.CD-20-1808

  • Reviews
    Decoding Cancer Biology One Cell at a Time
    L. Nicolas Gonzalez Castro, Itay Tirosh and Mario L. Suvà
    Cancer Discov April 1 2021 11 (4) 960-970; DOI:10.1158/2159-8290.CD-20-1376

  • Reviews
    Metastasis-Initiating Cells and Ecosystems
    Joan Massagué and Karuna Ganesh
    Cancer Discov April 1 2021 11 (4) 971-994; DOI:10.1158/2159-8290.CD-21-0010

Back to top
Previous
Cancer Discovery: 11 (4)
April 2021
Volume 11, Issue 4
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Editorial Board (PDF)

Sign up for alerts

Jump to

  • Editorial
  • In Focus
  • Perspective
  • Reviews
Advertisement
  • Most Cited
  • Most Read
Loading
  • The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data
  • Macrophages Regulate Response to Chemotherapy
  • Core Resistance Mechanisms and Genetic Evolution of Melanoma under BRAF Inhibitor Selection
  • Novel Mutant-Selective EGFR Inhibitor Overcomes Drug Resistance
  • EGFR Mediates RAF Inhibitor Resistance in BRAF-Mutant Colorectal Cancer
More...
  • Home
  • Alerts
  • Feedback
  • Privacy Policy
Facebook   Twitter   LinkedIn   YouTube   RSS

Articles

  • OnlineFirst
  • Current Issue
  • Past Issues

Info For

  • Authors
  • Subscribers
  • Advertisers
  • Librarians

About Cancer Discovery

  • About the Journal
  • Editors
  • Journal Sections
  • Permissions
  • Submit a Manuscript
AACR logo

Copyright © 2021 by the American Association for Cancer Research.

Cancer Discovery
eISSN: 2159-8290
ISSN: 2159-8274

Advertisement