Diacylglycerol Kinase α Is a Critical Signaling Node and Novel Therapeutic Target in Glioblastoma and Other Cancers

1Division of Neuro-Oncology, Department of Neurology, 2Division of Biostatistics, Department of Public Health, 3Departments of Pharmacology and 4Microbiology, University of Virginia Health System, Charlottesville, Virginia; and 5College of Nursing and Health Professions, University of Southern Indiana, Evansville, Indiana

1Division of Neuro-Oncology, Department of Neurology, 2Division of Biostatistics, Department of Public Health, 3Departments of Pharmacology and 4Microbiology, University of Virginia Health System, Charlottesville, Virginia; and 5College of Nursing and Health Professions, University of Southern Indiana, Evansville, Indiana

1Division of Neuro-Oncology, Department of Neurology, 2Division of Biostatistics, Department of Public Health, 3Departments of Pharmacology and 4Microbiology, University of Virginia Health System, Charlottesville, Virginia; and 5College of Nursing and Health Professions, University of Southern Indiana, Evansville, Indiana

1Division of Neuro-Oncology, Department of Neurology, 2Division of Biostatistics, Department of Public Health, 3Departments of Pharmacology and 4Microbiology, University of Virginia Health System, Charlottesville, Virginia; and 5College of Nursing and Health Professions, University of Southern Indiana, Evansville, Indiana

1Division of Neuro-Oncology, Department of Neurology, 2Division of Biostatistics, Department of Public Health, 3Departments of Pharmacology and 4Microbiology, University of Virginia Health System, Charlottesville, Virginia; and 5College of Nursing and Health Professions, University of Southern Indiana, Evansville, Indiana

1Division of Neuro-Oncology, Department of Neurology, 2Division of Biostatistics, Department of Public Health, 3Departments of Pharmacology and 4Microbiology, University of Virginia Health System, Charlottesville, Virginia; and 5College of Nursing and Health Professions, University of Southern Indiana, Evansville, Indiana

1Division of Neuro-Oncology, Department of Neurology, 2Division of Biostatistics, Department of Public Health, 3Departments of Pharmacology and 4Microbiology, University of Virginia Health System, Charlottesville, Virginia; and 5College of Nursing and Health Professions, University of Southern Indiana, Evansville, Indiana

1Division of Neuro-Oncology, Department of Neurology, 2Division of Biostatistics, Department of Public Health, 3Departments of Pharmacology and 4Microbiology, University of Virginia Health System, Charlottesville, Virginia; and 5College of Nursing and Health Professions, University of Southern Indiana, Evansville, Indiana

1Division of Neuro-Oncology, Department of Neurology, 2Division of Biostatistics, Department of Public Health, 3Departments of Pharmacology and 4Microbiology, University of Virginia Health System, Charlottesville, Virginia; and 5College of Nursing and Health Professions, University of Southern Indiana, Evansville, Indiana

1Division of Neuro-Oncology, Department of Neurology, 2Division of Biostatistics, Department of Public Health, 3Departments of Pharmacology and 4Microbiology, University of Virginia Health System, Charlottesville, Virginia; and 5College of Nursing and Health Professions, University of Southern Indiana, Evansville, Indiana

1Division of Neuro-Oncology, Department of Neurology, 2Division of Biostatistics, Department of Public Health, 3Departments of Pharmacology and 4Microbiology, University of Virginia Health System, Charlottesville, Virginia; and 5College of Nursing and Health Professions, University of Southern Indiana, Evansville, Indiana

1Division of Neuro-Oncology, Department of Neurology, 2Division of Biostatistics, Department of Public Health, 3Departments of Pharmacology and 4Microbiology, University of Virginia Health System, Charlottesville, Virginia; and 5College of Nursing and Health Professions, University of Southern Indiana, Evansville, Indiana