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Volume 4, Issue 5, pp. 522-526
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- Published first May 1, 2014.
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©2014 American Association for Cancer Research.
Author Information
- Authors' Affiliations:1Center for Applied Medical Research and 2Clinica Universidad de Navarra, Pamplona, Spain; 3Ovarian Cancer Research Center, University of Pennsylvania, Philadelphia, Pennsylvania; and 4Ludwig Cancer Research Center and 5Department of Oncology, CHUV, Lausanne, Switzerland
- Corresponding Authors:
Ignacio Melero, Center for Applied Medical Research and Clinica Univerisidad de Navarra, Av. Pio XII, 55, 31008 Pamplona, Spain. Phone: 34-948194700; Fax: 34-948194717; E-mail: imelero{at}unav.es; and George Coukos, Rue du Bugnon 27, CH-1011, Lausanne, Switzerland. E-mail: george.coukos{at}chuv.ch
May 2014
Volume 4, Issue 5
Volume 4, Issue 5
T-Cell and NK-Cell Infiltration into Solid Tumors: A Key Limiting Factor for Efficacious Cancer Immunotherapy
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- Article
- Abstract
- Introduction
- T-Cell Infiltration is Important for Overall Survival
- Molecular Tricks Played by Tumors to Attract Protumor Leukocytes and Repress Effector T-Cell Responses
- Blocking T-Cell Entrance and Functions in Cancer
- How to Modify T-Cell Infiltration to Help Immunotherapy
- Concluding Remarks
- Disclosure of Potential Conflicts of Interest
- Grant Support
- Footnotes
- References
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