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Volume 7, Issue 1, pp. 20-37
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History
- Received August 3, 2016
- Revision received November 3, 2016
- Accepted November 7, 2016
- Published first December 21, 2016.
Article Versions
- Previous version (December 21, 2016 - 05:48).
- You are viewing the most recent version of this article.
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©2016 American Association for Cancer Research.
Author Information
- 1Royal Marsden NHS Foundation Trust, London, United Kingdom.
- 2The Wellcome Trust/Cancer Research UK Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.
- 3The Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.
- 4The Institute of Cancer Research, London, United Kingdom.
- ↵*Corresponding Author:
Timothy A. Yap, Drug Development Unit, Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Downs Road, London SM2 5PT, United Kingdom. Phone: 44-20-8661-3539; Fax: 44-20-8642-7979; E-mail: timothy.yap{at}icr.ac.uk
January 2017
Volume 7, Issue 1
Volume 7, Issue 1
Targeting DNA Repair in Cancer: Beyond PARP Inhibitors
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- Article
- Abstract
- Introduction
- Targeting of DNA-Damage Sensor Proteins
- Targeting of DNA-Damage Signaling Proteins
- Targeting of DDR Effector Proteins and Repair Pathways
- Fine-Tuning the DDR
- Patient Selection
- Combination Strategies
- Future Perspectives and Conclusions
- Disclosure of Potential Conflicts of Interest
- Grant Support
- References
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