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Distinct Colorectal Cancer–Associated APC Mutations Dictate Response to Tankyrase Inhibition

Emma M. Schatoff, Sukanya Goswami, Maria Paz Zafra, Miguel Foronda, Michael Shusterman, Benjamin I. Leach, Alyna Katti, Bianca J. Diaz and Lukas E. Dow
Emma M. Schatoff
1Sandra and Edward Meyer Cancer Center, Department of Medicine, Weill Cornell Medicine, New York, New York.
2Weill Cornell/Rockefeller/Sloan Kettering Tri-I MD-PhD program, New York, New York.
3Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, New York.
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Sukanya Goswami
1Sandra and Edward Meyer Cancer Center, Department of Medicine, Weill Cornell Medicine, New York, New York.
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Maria Paz Zafra
1Sandra and Edward Meyer Cancer Center, Department of Medicine, Weill Cornell Medicine, New York, New York.
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Miguel Foronda
1Sandra and Edward Meyer Cancer Center, Department of Medicine, Weill Cornell Medicine, New York, New York.
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  • ORCID record for Miguel Foronda
Michael Shusterman
1Sandra and Edward Meyer Cancer Center, Department of Medicine, Weill Cornell Medicine, New York, New York.
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Benjamin I. Leach
1Sandra and Edward Meyer Cancer Center, Department of Medicine, Weill Cornell Medicine, New York, New York.
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Alyna Katti
1Sandra and Edward Meyer Cancer Center, Department of Medicine, Weill Cornell Medicine, New York, New York.
3Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, New York.
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Bianca J. Diaz
1Sandra and Edward Meyer Cancer Center, Department of Medicine, Weill Cornell Medicine, New York, New York.
3Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, New York.
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Lukas E. Dow
1Sandra and Edward Meyer Cancer Center, Department of Medicine, Weill Cornell Medicine, New York, New York.
3Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, New York.
4Department of Biochemistry, Weill Cornell Medicine, New York, New York.
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  • For correspondence: lud2005@med.cornell.edu
DOI: 10.1158/2159-8290.CD-19-0289 Published October 2019
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Article Information

Volume 9, Issue 10, pp. 1358-1371

DOI 
https://doi.org/10.1158/2159-8290.CD-19-0289
PubMed 
31337618

Published By 
American Association for Cancer Research
Print ISSN 
2159-8274
Online ISSN 
2159-8290
History 
  • Received March 8, 2019
  • Revision received July 10, 2019
  • Accepted July 18, 2019
  • Published first July 23, 2019.

Article Versions

  • Previous version (July 23, 2019 - 06:48).
  • Previous version (September 18, 2019 - 07:06).
  • You are viewing the most recent version of this article.
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©2019 American Association for Cancer Research.

Author Information

  1. Emma M. Schatoff1,2,3,
  2. Sukanya Goswami1,
  3. Maria Paz Zafra1,
  4. Miguel Foronda1,
  5. Michael Shusterman1,
  6. Benjamin I. Leach1,
  7. Alyna Katti1,3,
  8. Bianca J. Diaz1,3 and
  9. Lukas E. Dow1,3,4,*
  1. 1Sandra and Edward Meyer Cancer Center, Department of Medicine, Weill Cornell Medicine, New York, New York.
  2. 2Weill Cornell/Rockefeller/Sloan Kettering Tri-I MD-PhD program, New York, New York.
  3. 3Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, New York.
  4. 4Department of Biochemistry, Weill Cornell Medicine, New York, New York.
  1. ↵*Corresponding Author:
    Lukas E. Dow, Weill Cornell Medicine, Belfer Research Building, 413 E 69th Street, BB1318, New York, NY 10044. Phone: 646-962-6313; E-mail: lud2005{at}med.cornell.edu
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Cancer Discovery: 9 (10)
October 2019
Volume 9, Issue 10
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Distinct Colorectal Cancer–Associated APC Mutations Dictate Response to Tankyrase Inhibition
Emma M. Schatoff, Sukanya Goswami, Maria Paz Zafra, Miguel Foronda, Michael Shusterman, Benjamin I. Leach, Alyna Katti, Bianca J. Diaz and Lukas E. Dow
Cancer Discov October 1 2019 (9) (10) 1358-1371; DOI: 10.1158/2159-8290.CD-19-0289

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Distinct Colorectal Cancer–Associated APC Mutations Dictate Response to Tankyrase Inhibition
Emma M. Schatoff, Sukanya Goswami, Maria Paz Zafra, Miguel Foronda, Michael Shusterman, Benjamin I. Leach, Alyna Katti, Bianca J. Diaz and Lukas E. Dow
Cancer Discov October 1 2019 (9) (10) 1358-1371; DOI: 10.1158/2159-8290.CD-19-0289
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