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Cancer Discovery
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Tumor Neurobiology and the War of Nerves in Cancer

Sam Faulkner, Phillip Jobling, Brayden March, Chen Chen Jiang and Hubert Hondermarck
Sam Faulkner
1School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales, Australia.
2Hunter Medical Research Institute, University of Newcastle, New Lambton, New South Wales, Australia.
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Phillip Jobling
1School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales, Australia.
2Hunter Medical Research Institute, University of Newcastle, New Lambton, New South Wales, Australia.
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Brayden March
2Hunter Medical Research Institute, University of Newcastle, New Lambton, New South Wales, Australia.
3School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales, Australia.
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Chen Chen Jiang
2Hunter Medical Research Institute, University of Newcastle, New Lambton, New South Wales, Australia.
3School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales, Australia.
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Hubert Hondermarck
1School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales, Australia.
2Hunter Medical Research Institute, University of Newcastle, New Lambton, New South Wales, Australia.
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  • For correspondence: hubert.hondermarck@newcastle.edu.au
DOI: 10.1158/2159-8290.CD-18-1398 Published June 2019
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Article Information

Volume 9, Issue 6, pp. 702-710

DOI 
https://doi.org/10.1158/2159-8290.CD-18-1398
PubMed 
30944117

Published By 
American Association for Cancer Research
Print ISSN 
2159-8274
Online ISSN 
2159-8290
History 
  • Received November 29, 2018
  • Revision received February 13, 2019
  • Accepted February 19, 2019
  • Published first April 3, 2019.

Article Versions

  • Previous version (April 3, 2019 - 05:52).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2019 American Association for Cancer Research.

Author Information

  1. Sam Faulkner1,2,
  2. Phillip Jobling1,2,
  3. Brayden March2,3,
  4. Chen Chen Jiang2,3 and
  5. Hubert Hondermarck1,2,*
  1. 1School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales, Australia.
  2. 2Hunter Medical Research Institute, University of Newcastle, New Lambton, New South Wales, Australia.
  3. 3School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales, Australia.
  1. ↵*Corresponding Author:
    Hubert Hondermarck, University of Newcastle, LS3-35 Callaghan, NSW 2208, Australia. Phone: 61-2492-18830; Fax: 61-2492-18831; E-mail: hubert.hondermarck{at}newcastle.edu.au
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Cancer Discovery: 9 (6)
June 2019
Volume 9, Issue 6
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Tumor Neurobiology and the War of Nerves in Cancer
Sam Faulkner, Phillip Jobling, Brayden March, Chen Chen Jiang and Hubert Hondermarck
Cancer Discov June 1 2019 (9) (6) 702-710; DOI: 10.1158/2159-8290.CD-18-1398

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Tumor Neurobiology and the War of Nerves in Cancer
Sam Faulkner, Phillip Jobling, Brayden March, Chen Chen Jiang and Hubert Hondermarck
Cancer Discov June 1 2019 (9) (6) 702-710; DOI: 10.1158/2159-8290.CD-18-1398
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  • Article
    • Abstract
    • Introduction
    • Denervation and the Discovery of Nerve Involvement in Tumorigenesis
    • Tumor Axonogenesis: An Emerging Hallmark of Cancer
    • Sympathetic Nerves Drive Tumor Angiogenesis
    • Nerve–Cancer Stem Cell Connection: Toward a Yin–Yang Type of Neural Regulation
    • A Higher Regulation Level of Cancer Development
    • Clinical Implications of Tumor Axonogenesis
    • Conclusion
    • Disclosure of Potential Conflicts of Interest
    • Acknowledgments
    • Footnotes
    • References
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