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Tilsotolimod with Ipilimumab Drives Tumor Responses in Anti–PD-1 Refractory Melanoma
Cara Haymaker, Daniel H. Johnson, Ravi Murthy, Salah-Eddine Bentebibel, Marc I. Uemura, Courtney W. Hudgens, Houssein Safa, Marihella James, Robert H.I. Andtbacka, Douglas B. Johnson, Montaser Shaheen, Michael A. Davies, Shah Rahimian, Srinivas K. Chunduru, Denái R. Milton, Michael T. Tetzlaff, Willem W. Overwijk, Patrick Hwu, Nashat Gabrail, Sudhir Agrawal, Gary Doolittle, Igor Puzanov, Joseph Markowitz, Chantale Bernatchez, Adi Diab

Cancer Discovery Mar 2021, DOI: 10.1158/2159-8290.CD-20-1546
Preexisting and Post–COVID-19 Immune Responses to SARS-CoV-2 in Patients with Cancer
Tatjana Bilich, Malte Roerden, Yacine Maringer, Annika Nelde, Jonas S. Heitmann, Marissa L. Dubbelaar, Andreas Peter, Sebastian Hörber, Jens Bauer, Jonas Rieth, Marcel Wacker, Fiamma Berner, Lukas Flatz, Stefanie Held, Peter Brossart, Melanie Märklin, Philipp Wagner, Eva Erne, Reinhild Klein, Hans-Georg Rammensee, Helmut R. Salih, Juliane S. Walz

Cancer Discovery May 2021, DOI: 10.1158/2159-8290.CD-21-0191
Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis
Michael P. Kim, Xinqun Li, Jenying Deng, Yun Zhang, Bingbing Dai, Kendra L. Allton, Tara G. Hughes, Christian Siangco, Jithesh J. Augustine, Ya'an Kang, Joy M. McDaniel, Shunbin Xiong, Eugene J. Koay, Florencia McAllister, Christopher A. Bristow, Timothy P. Heffernan, Anirban Maitra, Bin Liu, Michelle C. Barton, Amanda R. Wasylishen, Jason B. Fleming, Guillermina Lozano

Cancer Discovery Apr 2021, DOI: 10.1158/2159-8290.CD-20-1228
Surface Proteomics Reveals CD72 as a Target for In Vitro–Evolved Nanobody-Based CAR-T Cells in KMT2A/MLL1-Rearranged B-ALL
Matthew A. Nix, Kamal Mandal, Huimin Geng, Neha Paranjape, Yu-Hsiu T. Lin, Jose M. Rivera, Makeba Marcoulis, Kristie L. White, Jeffrey D. Whitman, Sagar P. Bapat, Kevin R. Parker, Jonathan Ramirez, Anne Deucher, Paul Phojanokong, Veronica Steri, Faranak Fattahi, Byron C. Hann, Ansuman T. Satpathy, Aashish Manglik, Elliot Stieglitz, Arun P. Wiita

Cancer Discovery Mar 2021, DOI: 10.1158/2159-8290.CD-20-0242
Obesity-Dependent Adipokine Chemerin Suppresses Fatty Acid Oxidation to Confer Ferroptosis Resistance
Sze Kiat Tan, Iqbal Mahmud, Flavia Fontanesi, Michelle Puchowicz, Chase K.A. Neumann, Anthony J. Griswold, Rutulkumar Patel, Marco Dispagna, Hamzah H. Ahmed, Mark L. Gonzalgo, J. Mark Brown, Timothy J. Garrett, Scott M. Welford

Cancer Discovery Mar 2021, DOI: 10.1158/2159-8290.CD-20-1453
CARM1 Inhibition Enables Immunotherapy of Resistant Tumors by Dual Action on Tumor Cells and T Cells
Sushil Kumar, Zexian Zeng, Archis Bagati, Rong En Tay, Lionel A. Sanz, Stella R. Hartono, Yoshinaga Ito, Fieda Abderazzaq, Elodie Hatchi, Peng Jiang, Adam N. R. Cartwright, Olamide Olawoyin, Nathan D. Mathewson, Jason W. Pyrdol, Mamie Z. Li, John G. Doench, Matthew A. Booker, Michael Y. Tolstorukov, Stephen J. Elledge, Frédéric Chédin, X. Shirley Liu, Kai W. Wucherpfennig

Cancer Discovery Mar 2021, DOI: 10.1158/2159-8290.CD-20-1144
Genetic Determinants of EGFR-Driven Lung Cancer Growth and Therapeutic Response In Vivo
Giorgia Foggetti, Chuan Li, Hongchen Cai, Jessica A. Hellyer, Wen-Yang Lin, Deborah Ayeni, Katherine Hastings, Jungmin Choi, Anna Wurtz, Laura Andrejka, Dylan G. Maghini, Nicholas Rashleigh, Stellar Levy, Robert Homer, Scott N. Gettinger, Maximilian Diehn, Heather A. Wakelee, Dmitri A. Petrov, Monte M. Winslow, Katerina Politi

Cancer Discovery Jul 2021, 11 (7) 1736-1753; DOI: 10.1158/2159-8290.CD-20-1385
CD4 T Cell–Dependent Rejection of Beta-2 Microglobulin Null Mismatch Repair–Deficient Tumors
Giovanni Germano, Steve Lu, Giuseppe Rospo, Simona Lamba, Benoit Rousseau, Sonia Fanelli, Denise Stenech, Dung T. Le, John Hays, Maria Grazia Totaro, Vito Amodio, Rosaria Chilà, Anna Mondino, Luis A. Diaz, Federica Di Nicolantonio, Alberto Bardelli

Cancer Discovery Jul 2021, 11 (7) 1844-1859; DOI: 10.1158/2159-8290.CD-20-0987
PTHrP Drives Pancreatic Cancer Growth and Metastasis and Reveals a New Therapeutic Vulnerability
Jason R. Pitarresi, Robert J. Norgard, Anna M. Chiarella, Kensuke Suzuki, Basil Bakir, Varun Sahu, Jinyang Li, Jun Zhao, Benoît Marchand, Maximilian D. Wengyn, Antony Hsieh, Il-Kyu Kim, Amy Zhang, Karine Sellin, Vivian Lee, Shigetsugu Takano, Yoji Miyahara, Masayuki Ohtsuka, Anirban Maitra, Faiyaz Notta, Richard Kremer, Ben Z. Stanger, Anil K. Rustgi

Cancer Discovery Jul 2021, 11 (7) 1774-1791; DOI: 10.1158/2159-8290.CD-20-1098
Activity and Safety of Mobocertinib (TAK-788) in Previously Treated Non–Small Cell Lung Cancer with EGFR Exon 20 Insertion Mutations from a Phase I/II Trial
Gregory J. Riely, Joel W. Neal, D. Ross Camidge, Alexander I. Spira, Zofia Piotrowska, Daniel B. Costa, Anne S. Tsao, Jyoti D. Patel, Shirish M. Gadgeel, Lyudmila Bazhenova, Viola W. Zhu, Howard L. West, Tarek Mekhail, Ryan D. Gentzler, Danny Nguyen, Sylvie Vincent, Steven Zhang, Jianchang Lin, Veronica Bunn, Shu Jin, Shuanglian Li, Pasi A. Jänne

Cancer Discovery Jul 2021, 11 (7) 1688-1699; DOI: 10.1158/2159-8290.CD-20-1598

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