Advertisement

More articles from Research Articles

  • TBK1 is a Synthetic Lethal Target in Cancer with VHL Loss
    Lianxin Hu, Haibiao Xie, Xijuan Liu, Frances Potjewyd, Lindsey I James, Emily M. Wilkerson, Laura E. Herring, Ling Xie, Xian Chen, Johnny Castillo Cabrera, Kai Hong, Chengheng Liao, Xianming Tan, Albert S Baldwin, Kan Gong, Qing Zhang
    Cancer Discovery Jan 2019, CD-19-0837; DOI: 10.1158/2159-8290.CD-19-0837
  • Efficacy and Determinants of Response to HER Kinase Inhibition in HER2-Mutant Metastatic Breast Cancer
    Lillian M Smyth, Sarina A. Piha-Paul, Helen H Won, Alison M. Schram, Cristina Saura, Sherene Loi, Janice Lu, Geoffrey I. Shapiro, Dejan Juric, Ingrid A. Mayer, Carlos L. Arteaga, Macarena I de la Fuente, Adam M Brufksy, Iben Spanggaard, Morten Mau-Sorensen, Monica Arnedos, Victor Moreno, Valentina Boni, Joohyuk Sohn, Lee S. Schwartzberg, Xavier Gonzalez-Farre, Andres Cervantes, Francois-Clement Bidard, Alexander N Gorelick, Richard B. Lanman, Rebecca J. Nagy, Gary A Ulaner, Sarat Chandarlapaty, Komal Jhaveri, Elena I Gavrila, Catherine Zimel, S. Duygu Selcuklu, Myra Melcer, Aliaksandra Samoila, Yanyan Cai, Maurizio Scaltriti, Grace Mann, Feng Xu, Lisa D Eli, Melanie Dujka, Alshad S. Lalani, Richard Bryce, Jose Baselga, Barry S. Taylor, David B. Solit, Funda Meric-Bernstam, David M Hyman
    Cancer Discovery Jan 2019, CD-19-0966; DOI: 10.1158/2159-8290.CD-19-0966
  • Mutant BRAF and MEK inhibitors regulate the tumor immune microenvironment via pyroptosis
    Dan A Erkes, Weijia Cai, Ileine M Sanchez, Timothy J. Purwin, Corey Rogers, Conroy O Field, Adam C Berger, Edward J Hartsough, Ulrich Rodeck, Emad S Alnemri, Andrew E. Aplin
    Cancer Discovery Jan 2019, CD-19-0672; DOI: 10.1158/2159-8290.CD-19-0672
  • First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant FGF19 Signaling as a Driver Event in Hepatocellular Carcinoma
    Richard D. Kim, Debashis Sarker, Tim Meyer, Thomas Yau, Teresa Macarulla, Joong-Won Park, Su Pin Choo, Antoine Hollebecque, Max W. Sung, Ho-Yeong Lim, Vincenzo Mazzaferro, Joerg Trojan, Andrew X. Zhu, Jung-Hwan Yoon, Sunil Sharma, Zhong-Zhe Lin, Stephen L. Chan, Sandrine Faivre, Lynn G. Feun, Chia-Jui Yen, Jean-Francois Dufour, Daniel H. Palmer, Josep M. Llovet, Melissa Manoogian, Meera Tugnait, Nicolas Stransky, Margit Hagel, Nancy E. Kohl, Christoph Lengauer, Cori Ann Sherwin, Oleg Schmidt-Kittler, Klaus P. Hoeflich, Hongliang Shi, Beni B. Wolf, Yoon-Koo Kang
    Cancer Discovery Dec 2019, 9 (12) 1696-1707; DOI: 10.1158/2159-8290.CD-19-0555
  • Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene–Driven Myeloid Leukemia
    Cécile K. Lopez, Esteve Noguera, Vaia Stavropoulou, Elie Robert, Zakia Aid, Paola Ballerini, Chrystèle Bilhou-Nabera, Hélène Lapillonne, Fabien Boudia, Cécile Thirant, Alexandre Fagnan, Marie-Laure Arcangeli, Sarah J. Kinston, M'Boyba Diop, Bastien Job, Yann Lecluse, Erika Brunet, Loélia Babin, Jean Luc Villeval, Eric Delabesse, Antoine H.F.M. Peters, William Vainchenker, Muriel Gaudry, Riccardo Masetti, Franco Locatelli, Sébastien Malinge, Claus Nerlov, Nathalie Droin, Camille Lobry, Isabelle Godin, Olivier A. Bernard, Berthold Göttgens, Arnaud Petit, Françoise Pflumio, Juerg Schwaller, Thomas Mercher
    Cancer Discovery Dec 2019, 9 (12) 1736-1753; DOI: 10.1158/2159-8290.CD-18-1463
  • GATA3-Controlled Nucleosome Eviction Drives MYC Enhancer Activity in T-cell Development and Leukemia
    Laura Belver, Alexander Y. Yang, Robert Albero, Daniel Herranz, Francesco G. Brundu, S. Aidan Quinn, Pablo Pérez-Durán, Silvia Álvarez, Francesca Gianni, Marissa Rashkovan, Devya Gurung, Pedro P. Rocha, Ramya Raviram, Clara Reglero, Jose R. Cortés, Anisha J. Cooke, Agnieszka A. Wendorff, Valentina Cordó, Jules P. Meijerink, Raúl Rabadan, Adolfo A. Ferrando
    Cancer Discovery Dec 2019, 9 (12) 1774-1791; DOI: 10.1158/2159-8290.CD-19-0471
  • Targeting CD39 in Cancer Reveals an Extracellular ATP- and Inflammasome-Driven Tumor Immunity
    Xian-Yang Li, Achim K. Moesta, Christos Xiao, Kyohei Nakamura, Mika Casey, Haiyan Zhang, Jason Madore, Ailin Lepletier, Amelia Roman Aguilera, Ashmitha Sundarrajan, Celia Jacoberger-Foissac, Clifford Wong, Tracy dela Cruz, Megan Welch, Alana G. Lerner, Bradley N. Spatola, Vanessa B. Soros, John Corbin, Ana C. Anderson, Maike Effern, Michael Hölzel, Simon C. Robson, Rebecca L. Johnston, Nicola Waddell, Corey Smith, Tobias Bald, Nishamol Geetha, Courtney Beers, Michele W. L. Teng, Mark J. Smyth
    Cancer Discovery Dec 2019, 9 (12) 1754-1773; DOI: 10.1158/2159-8290.CD-19-0541
  • The Phenotypes of Proliferating Glioblastoma Cells Reside on a Single Axis of Variation
    Lin Wang, Husam Babikir, Sören Müller, Garima Yagnik, Karin Shamardani, Francisca Catalan, Gary Kohanbash, Beatriz Alvarado, Elizabeth Di Lullo, Arnold Kriegstein, Sumedh Shah, Harsh Wadhwa, Susan M. Chang, Joanna J. Phillips, Manish K. Aghi, Aaron A. Diaz
    Cancer Discovery Dec 2019, 9 (12) 1708-1719; DOI: 10.1158/2159-8290.CD-19-0329
  • Polyunsaturated Fatty Acids from Astrocytes Activate PPARγ Signaling in Cancer Cells to Promote Brain Metastasis
    Yongkang Zou, Andrea Watters, Nan Cheng, Caroline E. Perry, Ke Xu, Gretchen M. Alicea, Joshua L.D. Parris, Ezra Baraban, Pulak Ray, Anupma Nayak, Xiaowei Xu, Meenhard Herlyn, Maureen E. Murphy, Ashani T. Weeraratna, Zachary T. Schug, Qing Chen
    Cancer Discovery Dec 2019, 9 (12) 1720-1735; DOI: 10.1158/2159-8290.CD-19-0270
  • Histone Lysine Methylation Dynamics Control EGFR DNA Copy Number Amplification
    Thomas L Clarke, Ran Tang, Damayanti Chakraborty, Capucine Van Rechem, Fei Ji, Sweta Mishra, Anqi Ma, H Umit Kaniskan, Jian Jin, Michael S. Lawrence, Ruslan I. Sadreyev, Johnathan R. Whetstine
    Cancer Discovery Jan 2019, CD-19-0463; DOI: 10.1158/2159-8290.CD-19-0463

Pages