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Metastasis-Initiating Cells and Ecosystems
Joan Massagué, Karuna Ganesh

Cancer Discovery Apr 2021, 11 (4) 971-994; DOI: 10.1158/2159-8290.CD-21-0010
Artificial Intelligence in Cancer Research and Precision Medicine
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Cancer Discovery Apr 2021, 11 (4) 900-915; DOI: 10.1158/2159-8290.CD-21-0090
The Future of Clinical Trial Design in Oncology
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Cancer Discovery Apr 2021, 11 (4) 822-837; DOI: 10.1158/2159-8290.CD-20-1301
Overcoming Resistance to Tumor-Targeted and Immune-Targeted Therapies
Mihaela Aldea, Fabrice Andre, Aurelien Marabelle, Semih Dogan, Fabrice Barlesi, Jean-Charles Soria

Cancer Discovery Apr 2021, 11 (4) 874-899; DOI: 10.1158/2159-8290.CD-20-1638
Liquid Biopsy: From Discovery to Clinical Application
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Cancer Discovery Apr 2021, 11 (4) 858-873; DOI: 10.1158/2159-8290.CD-20-1311
Decoding Cancer Biology One Cell at a Time
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Cancer Discovery Apr 2021, 11 (4) 960-970; DOI: 10.1158/2159-8290.CD-20-1376
Therapeutic Targeting of the Tumor Microenvironment
Leire Bejarano, Marta J.C. Jordāo, Johanna A. Joyce

Cancer Discovery Apr 2021, 11 (4) 933-959; DOI: 10.1158/2159-8290.CD-20-1808
Tracking Cancer Evolution through the Disease Course
Chris Bailey, James R.M. Black, James L. Reading, Kevin Litchfield, Samra Turajlic, Nicholas McGranahan, Mariam Jamal-Hanjani, Charles Swanton

Cancer Discovery Apr 2021, 11 (4) 916-932; DOI: 10.1158/2159-8290.CD-20-1559
The Next Decade of Immune Checkpoint Therapy
Padmanee Sharma, Bilal A. Siddiqui, Swetha Anandhan, Shalini S. Yadav, Sumit K. Subudhi, Jianjun Gao, Sangeeta Goswami, James P. Allison

Cancer Discovery Apr 2021, 11 (4) 838-857; DOI: 10.1158/2159-8290.CD-20-1680
Opportunities and Challenges in Drug Development for Pediatric Cancers
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