PT  - JOURNAL ARTICLE
AU  - Rejto, Paul A.
AU  - Abraham, Robert T.
TI  - <em>MTOR</em> Mutations in the Crosshairs of Targeted Therapy
AID  - 10.1158/2159-8290.CD-14-0332
DP  - 2014 May 01
TA  - Cancer Discovery
PG  - 513--515
VI  - 4
IP  - 5
4099  - http://cancerdiscovery.aacrjournals.org/content/4/5/513.short
4100  - http://cancerdiscovery.aacrjournals.org/content/4/5/513.full
SO  - CANCER DISCOVERY2014 May 01; 4
AB  - Summary: The identification of genetic lesions that affect tumor sensitivity to targeted therapies is a major objective of precision medicine. Two reports in this issue combine tumor genome analyses with functional characterization to uncover activating mutations in MTOR that confer sensitivity to a clinically used mTOR inhibitor. Cancer Discov; 4(5); 513–5. ©2014 AACR. See related article by Wagle et al., p. 546 See related article by Grabiner et al., p. 554