PT - JOURNAL ARTICLE AU - Teng, Michele W.L. AU - Khanna, Rajiv AU - Smyth, Mark J. TI - Checkpoint Immunotherapy: Picking a Winner AID - 10.1158/2159-8290.CD-16-0694 DP - 2016 Aug 01 TA - Cancer Discovery PG - 818--820 VI - 6 IP - 8 4099 - http://cancerdiscovery.aacrjournals.org/content/6/8/818.short 4100 - http://cancerdiscovery.aacrjournals.org/content/6/8/818.full SO - Cancer Discov2016 Aug 01; 6 AB - Summary: Robust biomarkers of response that predict which patients will or will not respond to immune checkpoint blockade need to be identified. New data suggest that the presence of an adaptive immune signature in the tumor biopsies of patients with melanoma early on therapy compared to pretreatment can identify responders from nonresponders. Cancer Discov; 6(8); 818–20. ©2016 AACR.See related article by Chen et al., p. 827.