PT - JOURNAL ARTICLE AU - Snyder, Alexandra AU - Wolchok, Jedd D. TI - Successful Treatment of a Patient with Glioblastoma and a Germline <em>POLE</em> Mutation: Where Next? AID - 10.1158/2159-8290.CD-16-1056 DP - 2016 Nov 01 TA - Cancer Discovery PG - 1210--1211 VI - 6 IP - 11 4099 - http://cancerdiscovery.aacrjournals.org/content/6/11/1210.short 4100 - http://cancerdiscovery.aacrjournals.org/content/6/11/1210.full SO - Cancer Discov2016 Nov 01; 6 AB - Summary: Hypermutation and elevated neoantigen count in glioblastoma occurred in a patient harboring a germline POLE mutation and are associated with a clinical and antitumor immune response to PD-1 blockade. Cancer Discov; 6(11); 1210–11. ©2016 AACR.See related article by Johanns et al., p. 1230.