RT Journal Article
SR Electronic
T1 Debugging the Black Box
JF Cancer Discovery
JO Cancer Discov
FD American Association for Cancer Research
SP 250
OP 251
DO 10.1158/2159-8290.CD-17-0070
VO 7
IS 3
A1 Yang, James C.
YR 2017
UL http://cancerdiscovery.aacrjournals.org/content/7/3/250.abstract
AB Summary: A better understanding of the mechanisms by which tumor rejection succeeds and fails is needed to improve immunotherapies. Here, Anagnostou and colleagues find that mutations predicted to be the most immunogenic are preferentially lost when cancer progresses through checkpoint blockade. Cancer Discov; 7(3); 250–1. ©2017 AACR.See related article by Anagnostou et al., p. 264.