PT - JOURNAL ARTICLE ED - , TI - Three Drugs Approved for Urothelial Carcinoma by FDA AID - 10.1158/2159-8290.CD-NB2017-071 DP - 2017 Jul 01 TA - Cancer Discovery PG - 659--660 VI - 7 IP - 7 4099 - http://cancerdiscovery.aacrjournals.org/content/7/7/659.short 4100 - http://cancerdiscovery.aacrjournals.org/content/7/7/659.full SO - Cancer Discov2017 Jul 01; 7 AB - The FDA has approved one PD-1 checkpoint inhibitor, pembrolizumab, and two PD-L1 checkpoint inhibitors, avelumab and durvalumab, to treat metastatic urothelial carcinoma in patients whose disease continues to progress despite platinum-based chemotherapy. This brings the total number of checkpoint inhibitors for the disease to five, prompting questions about how best to use them.