RT Journal Article
SR Electronic
T1 FDA Offers Advice on Trial Design
JF Cancer Discovery
JO Cancer Discov
FD American Association for Cancer Research
SP OF1
OP OF1
DO 10.1158/2159-8290.CD-NB2019-115
VO 9
IS 11
YR 2019
UL http://cancerdiscovery.aacrjournals.org/content/9/11/OF1.abstract
AB The FDA recently released a final guidance that outlines the specific situations in which placebos can be used in oncology clinical trials—and in which patients and investigators should be unblinded. Oncologists consider the guidance useful, but note that it largely aligns with how oncology trials are already conducted.