PT  - JOURNAL ARTICLE
AU  - Carter, Hannah
TI  - Loss of RNA-Binding Protein RBMS1 Promotes a Metastatic Transcriptional Program in Colorectal Cancer
AID  - 10.1158/2159-8290.CD-20-0993
DP  - 2020 Sep 01
TA  - Cancer Discovery
PG  - 1261--1262
VI  - 10
IP  - 9
4099  - http://cancerdiscovery.aacrjournals.org/content/10/9/1261.short
4100  - http://cancerdiscovery.aacrjournals.org/content/10/9/1261.full
SO  - Cancer Discov2020 Sep 01; 10
AB  - Summary: Yu and colleagues combined computational and experimental techniques to identify a new post-transcriptional regulator of metastatic potential in colon cancer. This study reveals that the RNA-binding protein RBMS1 is a positive regulator of mRNA stability for multiple genes, including the tumor suppressor AKAP12 and a WNT pathway interacting protein, SDCBP, and its loss is a common event associated with poor prognosis.See related article by Yu et al., p. 1410.