Table 4.

SNPs from NR4A1 targets and upstream and downstream regulators (additive model)

CHRSNPBPOR (95% CI)aP valueMAFLocationGene
1rs566421267822531.23 (1.02–1.48)0.0290.38Flanking_3UTRRPS6KA1
1rs101591801547469480.83 (0.69–1.00)0.0500.48Flanking_5UTRMEF2D
2rs134289681569008591.30 (1.02–1.66)0.0340.16Flanking_5UTRNR4A2
4rs76564111548471051.23 (1.00–1.50)0.0480.26Flanking_3UTRTLR2
5rs104826421427082241.28 (1.00–1.63)0.0470.17Flanking_3UTRNR3C1
12rs2701129507157440.63 (0.48–0.83)0.0010.13Flanking_5UTRNR4A1
12rs2701124507344240.58 (0.41–0.82)0.0020.08CodingNR4A1
15rs325383980725691.28 (1.05–1.57)0.0160.29Flanking_3UTRMEF2A
17rs207848675238080.71 (0.51–1.00)0.0500.08IntronTP53
18rs4987856589444741.44 (1.07–1.94)0.0160.103UTRBCL2
18rs1977971591191741.28 (1.06–1.53)0.0090.46IntronBCL2
18rs11152377591234260.83 (0.69–0.99)0.0360.42IntronBCL2
18rs1462129591318511.26 (1.05–1.51)0.0130.48IntronBCL2
18rs1801018591368590.82 (0.69–0.99)0.0370.43CodingBCL2
19rs810169640664520.60 (0.41–0.89)0.0110.06IntronMAP2K2
19rs4808100177924971.24 (1.03–1.49)0.0200.37IntronINSL3
20rs6063022354267411.33 (1.03–1.71)0.0270.15IntronSRC
  • Abbreviations: CHR, chromosome; CI, confidence interval; MAF, multiple alignment format.

  • a Univariate analysis.