Table 1.

SNPs with lowest P values identified during GWAS genotyping: NSABP P-1 and P-2

Conditional logistic regression for matched designUnconditional logistic regression
Adjusted for 9 eigenvectorsUnadjustedAdjusted for 9 eigenvectors
MAFOR (95% CI)
SNPChromosomeSNP position (bp)Gene name (±50 kb)Gene position (bp)CasesControlsPPP
rs80601571649830204ZNF42349521435-498918300.390.470.7 (0.6–0.81)2.12E-062.86E-061.11E-06
rs95103511323384332N/AN/A0.120.190.61 (0.5–0.75)2.76E-065.11E-064.52E-06
rs10030044 4157011923CTSO156845270-1568750630.450.361.42 (1.23–1.65)3.63E-063.16E-068.49E-07
rs110764991649828405ZNF42349521435-498918300.390.470.71 (0.61–0.82)3.70E-064.46E-061.87E-06
rs11999029 911860446N/AN/A0.160.111.64 (1.33–2.02)3.76E-067.20E-065.34E-06
rs4256192 4157016504CTSO156845270-1568750630.390.311.44 (1.23–1.68)4.27E-063.10E-062.46E-06
rs11925220 3133569777RAB6B133543083-1336146800.540.461.39 (1.21–1.61)6.17E-069.63E-069.64E-06
rs7853211 911830974N/AN/A0.190.131.55 (1.28–1.88)6.94E-068.98E-066.49E-06
rs10960317 911848457N/AN/A0.160.111.61 (1.31–1.99)7.01E-061.34E-059.69E-06
rs16928160 911830879N/AN/A0.170.121.59 (1.3–1.94)7.28E-061.10E-057.33E-06
rs7832497 8104126852AK001351104133260-1041475190.20.270.68 (0.57–0.8)9.98E-061.84E-052.52E-05

Abbreviations: bp, base position; CI, confidence interval.