Table 2.

Confirmed response per RECIST tumor assessments for all patients and by mutation status: concurrent regimen

nAll patientsaT790M+bT790MbDel 19L858R
Total treated12671537841
RECIST response8954334834
 ORc (CR/PR)3723132314
 Unconfirmed OR54131
 CR/PR <35 d followed by PD31230
 SD <35 d followed by PD1587141
  • aIncludes 2 patients for whom T790M status was unknown due to tissue samples insufficient for testing.

  • bAvailable for 124 of 126 treated patients.

  • cAll ORs were PRs; no CRs were observed.

    Abbreviation: d, days.