Table 1.

Recurrent genes with enriched splicing motif mutations

Gene nameGBM splicing motif GVsGBM splicing motif SMsNeuroblastoma splicing motif GVsNeuroblastoma splicing motif SMs
MOXD2P0001-chr7:141944631 C>T
1-chr7:141943454 A>C
CGB7001-chr19:49558080 G/C2-chr19:49558080 G>C
DYNLRB11-chr20:33104296 C/G2-chr20:33121706 C>T02-chr20:33121706 C>T
NPIPA11-chr16:15040359 G/A4-chr16:15040359 G>A01-chr16:15040359 G>A
1-chr16:15031765 G>C
LOC10050581103 chr5:117618623 C>T00
TRAM2-AS103 chr6:52445058 T>G00
AIMP102-chr4:107260426 G>T01- chr4:107260426 G>T
PRDM1202-chr9:133545135 G>A00
TIGD702-chr16:3353982 A>G00
FBXO4502-chr3:196310237 C>T00
SLC4A102-chr17:42342896 C>A00
ARHGAP291-chr1:94677742 G/C2-chr1:94678897 G>A00
LOC1001280061-chr17:12681207 G/A1-chr17:12679656 T>G00
1-chr17:12673734 C>T
LOC4408961-chr9:69180408 G/A1-chr9:69179798 T>C00
1-chr9:69180519 C>G
STXBP51-chr6:147648825 G/C2-chr6:147693778 T>C00
TNNI21-chr11:1860346 T/G1-chr11:1860346 T>G00
1-chr11:1862029 G>A

NOTE: Enrichment was identified by taking the ratio of samples with somatic mutations (SM) within splicing motifs to samples with germline variants (GV) within splicing motifs.