Table 1.

Genomic profiling and microsatellite status for each patient on study according to treatment response

BRAFKRASNRASPIK3CAAKTMSI-HBest response
1V600EWild-typeWild-typeWild-typeWild-type(Not tested)SD
2V600EWild-typeWild-type(Not tested)(Not tested)MSI-HPR
3V600EWild-typeWild-typeWild-typeWild-typeMSSPR
4V600EWild-typeWild-type(Not tested)(Not tested)MSSSD
5V600EWild-typeWild-typeWild-typeWild-typeMSSPD
6V600EWild-typeWild-typeWild-typeWild-typeMSSPR
7V600EWild-typeWild-typeWild-typeWild-typeMSSSD
8V600EWild-typeWild-typeWild-typeWild-typeMSSSD
9V600EWild-typeWild-typeWild-typeWild-typeMSI-HPR
10V600EWild-typeWild-typeWild-typeWild-typeMSSN/A
11V600EWild-typeWild-typeWild-typeWild-type(Not tested)SD
12V600EWild-typeWild-typeWild-typeWild-typeMSSSD
13V600EWild-typeWild-typeWild-typeWild-type(Not tested)SD
14V600EWild-typeWild-typeWild-typeWild-type(Not tested)PR
15V600EWild-typeWild-typeWild-typeWild-type(Not tested)SD
16V600EWild-typeWild-typeWild-typeWild-typeMSSSD
17V600EWild-typeWild-typeWild-typeWild-typeMSSPR
18V600EWild-typeWild-typeWild-typeWild-typeMSSSD
19V600EWild-typeWild-typeH1047RWild-typeMSI-HPD
  • Abbreviations: MSI-H, microsatellite-high; MSS, microsatellite stable; PD, progressive disease; PR, partial response; SD, stable disease; N/A, not assessed.