Table 1A.

Demographics at diagnosis by EGFR amplification status across the entire U of C cohort

CharacteristicEGFR amplifiedEGFR nonamplifiedP
Number of patients (%)19 (5)344 (95)<2.2 × 10−16
Median age, y (range)64 (37–77)63 (16–91)0.97
Male sex, n (%)16 (84)238 (69)0.20
Disease site, n (%)
 Esophagus/GEJ12 (63)183 (53)0.54
 Gastric7 (37)161 (47)
Tumor grade, n (%)
 Well differentiated0 (0)13 (4)0.557
 Moderately differentiated3 (16)89 (26)
 Poorly differentiated15 (79)229 (67)
 Unknown1 (5)13 (4)
Stage at diagnosis, n (%)
 I0 (0)35 (10)0.11
 II0 (0)43 (13)
 III4 (21)93 (27)
 IV15 (79)172 (50)
 Unknown0 (0)1 (0)
HER2, n (%)
 Positive5 (26)81 (24)0.91
 Negative12 (63)212 (62)
 Equivocal0 (0)17 (5)
 Unknown2 (11)34 (10)
Race, n (%)
 Caucasian15 (79)250 (73)0.68
 African American2 (11)58 (17)
 Asian1 (5)27 (8)
 Hispanic1 (5)9 (3)
  • Abbreviation: U of C, University of Chicago.