Table 2B.

PD-L1 expression in the GEA Foundation Medicine cohort, by EGFR amplification status

All GEAEGJGastricGEA EGFR WTGEA EGFR amp
Cases with PD-L1 IHC, n63237725559141
PD-L1 tumor (%)
 High positive20 (3)12 (3)8 (3)20 (3)0
 Low positive89 (14)56 (15)33 (13)84 (14)5 (12)
 Negative523 (83)309 (82)214 (84)487 (82)36 (88)
PD-L1 TILs (%)
 High positive1 (0.2)01 (0.4)1 (0.2)0
 Low positive110 (17)72 (19)38 (15)105 (18)5 (12)
 Negative521 (82)305 (81)216 (85)485 (82)36 (88)
PD-L1 CPS (%)
 Positive (≥1%)166 (26)106 (28)60 (24)159 (27)7 (17)
 Negative466 (74)271 (72)195 (76)432 (73)34 (83)
  • Abbreviation: WT, wild-type.