Table 2.

Drug-related AEs that occurred in at least 10% of patients

Drug-related AEs
SD-101 dose1 mg (n = 10)2 mg (n = 3)4 mg (n = 3)8 mg (n = 13)Total (n = 29)
Grade1/231/231/231/231/23All
Malaise9 (90)02 (67)03 (100)08 (62)5 (38)22 (76)5 (17)27 (93)
Chills8 (80)02 (67)03 (100)09 (69)4 (31)22 (76)4 (14)26 (90)
Fatigue7 (70)03 (100)03 (100)010 (77)2 (15)23 (79)2 (7)25 (86)
Headache7 (70)1 (10)3 (100)03 (100)07 (54)4 (31)20 (69)5 (17)25 (86)
Myalgia6 (60)03 (100)03 (100)010 (77)3 (23)22 (76)3 (10)25 (86)
Fever4 (40)01 (33)02 (67)012 (92)019 (66)019 (66)
Nausea2 (20)01 (33)0008 (62)011 (38)011 (38)
Diarrhea3 (30)0001 (33)04 (31)08 (28)08 (28)
Injection-site erythema4 (40)0001 (33)03 (23)08 (28)08 (28)
Vomiting001 (33)0005 (38)06 (21)06 (21)
Neutropenia1 (10)1 (10)00002 (15)1 (8)3 (10)2 (7)5 (17)
Decreased appetite2 (20)000002 (15)04 (14)04 (14)
Injection-site swelling3 (30)01 (33)000004 (14)04 (14)
Night sweats2 (20)0001 (33)0003 (10)03 (10)
Sore throat1 (10)000002 (15)03 (10)03 (10)
Thrombocytopenia001 (33)0002 (15)03 (10)03 (10)