Table 2.

T-DM1–related adverse events

Adverse eventsGrade 1 N (%)Grade 2 N (%)Grade 3 N (%)Total
Elevated AST or ALT28 (57)3 (6)31 (63)
Thrombocytopenia13 (27)1 (2)1 (2)15 (31)
Fatigue6 (12)2 (4)8 (16)
Nausea14 (29)14 (29)
Infusion reaction2 (4)5 (10)7 (14)
Anorexia3 (6)2 (4)5 (10)
Anemia1 (1)3 (6)1 (2)5 (10)
  • NOTE: Treatment-related adverse events with total frequencies of greater than 10%, according to National Cancer Institute Common Terminology Criteria for Adverse Events version 4.1 (CTCAE v4.1). There were no grade 4 or 5 adverse events.